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제목 Ella 등록일 2018-12-11 17:07:02

Ella

Your Next Generation ELISA

Ella's combination of performance and workflow brings your immunoassays to the next level. In just 90 minutes you get highly reproducible validated assay data with no manual steps. The assay performance behind that data includes sub-picogram level sensitivity, 4+ logs of dynamic range and reproducibility that rivals the best laboratory automation. All in a compact package that doesn’t break your budget or your lab bench.

Ella

WHAT IMMUNOASSAY PROBLEM CAN ELLA SOLVE FOR YOU?

I want to spend less hands-on time doing the immunoassay

You're in a race to make that next discovery, and Ella can help you get there faster. There's no need to split your time between running assays in the lab and analyzing answers at your desk. Simply add your sample and buffers to the Simple Plex cartridge, put it in Ella and start your run. There's only 10-15 minutes of hands-on assay prep time, and she gives you fully analyzed answers in an hour!

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

ELLA: 10-15 MIN SETUP, 1 HR FOR ANSWERS

I want flexibility with my plex

Need the flexibility to pick your plex or an upgrade path that doesn't lock you into a platform when your assays change? Ella has three Simple Plex cartridges that let you choose what you want to do, when you want to do it. Use the 32x4 and 16x4 formats for multiplexing, or the 72x1 for single-analyte assays. Use our Kit Builder tool to build your panel online!

I need single digit CVs

Getting good immunoassay reproducibility is tricky with all the multiple, manual steps. Automation instrumentation adds to it too. With Ella, everything happens on the Simple Plex cartridge so each immunoassay is run the same way every time. There aren't any manual steps, washes or reagent additions.

Ella's also volume-independent. There's none of the variability that comes with pipetting error volume discrepancies. She precisely controls the volume on every assay, so every sample is handled the same way.

Ella uses fluorescence detection so she also stretches what you can do with your samples. Now not only can you detect low endogenous levels of proteins, but you can measure those proteins across a wider and more sensitive detection range too.

Translation? Way less variability, better sensitivity, large reading range and you'll get low single-digit CVs.

TOP:  Reproducibility comparison for IL-10 near LLOQ.
BOTTOM:  Sensitivity and dynamic range comparison between Ella and traditional ELISA.

I need to transfer my immunoassay and get the same results

When it's time to develop and transfer your immunoassay to other labs, sites or a contract research organization, Ella makes it easy. Because Simple Plex assays are precisely controlled in the cartridge, there's no chance for pipetting errors. You'll get the same reproducible answers across multiple users and multiple sites. Simply put, you'll get consistent answers anywhere, by anyone on any Ella.

FIGURE 2.  Testing across 3 sites, 11 users and 9 Ella instruments. Four different assays were processed for CCL2, IL-6, TNF α and VEGF-A. Eight unique serum samples with 2 controls for a total of 704 answers.

My current immunoassay uses too much sample

Given you spend hours collecting it or thousands of dollars to get it—that sample is the most precious thing in your lab. Ella's a sample conservationist. She only needs 50 µL of diluted sample and given her high sensitivity that equates to 2.5-25 µL of your precious sample. For each small aliquot of precious sample, the microfluidic design produces 3 answers, one for each of the three Glass Nano Reactors.

I want correlation to my existing immunoassay

Did we say Simple Plex assays are powered by R&D Systems and are correlated against Quantikine® assays? That means you'll get the quality you already know and trust plus all the power Ella and Simple Plex assays can give you. So when you're ready to make the move to Ella, you can do it with confidence.

TECHNOLOGY & APPLICATIONS

Ella does immunoassays in a microfluidic Simple Plex cartridge. It's like using a pre-kitted immunoassay, except everything's pre-loaded on the cartridge—even the calibration curve! All you need to do is add your sample and buffers and put the cartridge in Ella.

The immunoassay part works like this: sample runs through a microfluidic channel that binds your protein of interest. Next, Ella washes off unbound analyte and adds a detection reagent. Because each channel has three Glass Nano Reactors (GNRs) coated with a capture antibody, you get triplicate answers for each sample. Answers are then generated from the factory-calibrated standard curve that comes with every cartridge. Sound familiar? It's the same immunoassay you're used to, just without the errors that come with traditional assays.

DESCRIPTIONSPECIFICATION
Sample Volume Required2.5 to 25 µL
Analytes per SampleUp to 4 independent Simple Plex assays per sample
Throughput72 samples with 1 analyte, or 16 samples with up to 4 analytes
Hands-on Time5 minutes
Time to Result60 minutes
SensitivitySub-picogram/mL
ReproducibilitySingle-digit CVs, results in triplicate
Dynamic Range4-5 logs
Cross-reactivityN/A, Simple Plex assays are run in parallel in individual channels

 

공지사항
Cat No. 제품명
600-100 Ella System
600-102 Simple Plex demo kit
600-120 Ella System (w/o computer)
600-151 Simple Plex System Software, 21 CFR part 11
600-150 Simple Plex Explorer Analysis Software, single license
SPCKA-XX-XXXXXX Simple Plex Cartridge Kit for 16 samples, 4 analytes for use with a novel Sample Type
SPCKA-HF-XXXXXX Simple Plex Cartridge Kit for 16 samples, 4 analytes for use with Human CSF
SPCKA-PS-xxxxxx Simple Plex Cartridge Kit for 16 samples, 4 analytes for use with Human Plasma/Serum.
SPCKA-MF-XXXXXX Simple Plex Cartridge Kit for 16 samples, 4 analytes for use with Mouse CSF
SPCKA-RF-XXXXXX Simple Plex Cartridge Kit for 16 samples, 4 analytes for use with Rat CSF
SPCKA-RP-XXXXXX Simple Plex Cartridge Kit for 16 samples, 4 analytes for use with Rat Plasma/Serum
SPCKA-RU-XXXXXX Simple Plex Cartridge Kit for 16 samples, 4 analytes for use with Rat Urine
SPCKC-PS-XXXXXX Simple Plex Cartridge Kit for 32 samples, 4 analytes for use with Human Plasma/Serum.
SPCKC-MP-XXXXXX Simple Plex Cartridge Kit for 32 samples, 4 analytes for use with Mouse Plasma/Serum.
SPCKB-CL-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Cell Lysate
SPCKB-CS-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Cell Supernatant. 
SPCKB-HF-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Human CSF
SPCKB-HU-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Human Urine
SPCKB-MC-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Mouse Cell Lysate
SPCKB-MF-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Mouse CSF
SPCKB-MP-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Mouse Plasma/Serum
SPCKB-MU-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Mouse Urine
SPCKB-PS-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Plasma/Serum
SPCKB-RF-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Rat CSF
SPCKB-RU-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Rat Urine
SPCKB-TR-XXXXXX Simple Plex Cartridge Kit for 72 samples, 1 analyte for use with Tears
895151 Calibrator Diluent RD5P
898243 Human 14-3-3 zeta
898762 Human Amphiregulin
898070 Human Angiogenin
894945 Human Angiopoietin-1
898056 Human Angiopoietin-2
898432 Human Angiopoietin-like 4
898571 Human ASC
898318 Human AXL
898400 Human B7-H1/PD-L1
898071 Human BAFF
898628 Human BCMA/TNFRSF17
898072 Human BDNF
894946 Human BMP-2
898057 Human BMP-4
898058 Human BMP-9
898518 Human B-NGF
898073 Human CA-125, Lyophilized Control
898074 Human CA9
898569 Human Caspase-1
894947 Human CCL1/I-309
898481 Human CCL13/MCP-4
898430 Human CCL16/HCC-4
898075 Human CCL17/TARC
894948 Human CCL2/MCP-1
898479 Human CCL20/MIP-3a
898076 Human CCL22/MDC
898059 Human CCL3/MIP-1a
898077 Human CCL4/MIP-1b
898536 Human CCL7/MCP-3
898538 Human CCL8/MCP-2
898078 Human CD14
898163 Human CD163
898282 Human CD21
898079 Human CD25/IL-2ra
898284 Human CD27/TNFRSF7
898323 Human CD40/TNFRSF5
898169 Human Chitinase-3L1
898426 Human Chromogranin A
898981 Human Clusterin
898620 Human COMP (TSP-5)
898080 Human CRP
898495 Human CTGF
898143 Human CX3CL1/Fractalkine
894949 Human CXCL10/IP-10
898082 Human CXCL12/SDF-1a
898173 Human CXCL13/BLC/BCA-1
898253 Human CXCL5/ENA-78
894951 Human CXCL9/MIG
898932 Human Cyr61
898175 Human Cystatin C
898768 Human Cytokeratin 18/CK18/KRT
898616 Human DcR3
898123 Human DKK-1
898083 Human E-CAD
894952 Human EGF
898084 Human Endoglin/CD105
898177 Human Endothelin-1
898272 Human Enolase-2
898540 Human Eotaxin-3
898085 Human Epo
898120 Human ErbB2
898179 Human E-Selectin
898618 Human FAP
898895 Human FAS/TNFRSF6
898923 Human Ferritin
898183 Human FGF-19
898185 Human FGF-21
898734 Human FGF-7/KGF
898087 Human Follistatin
898088 Human Galectin-3
898060 Human GAS6
894953 Human G-CSF
898090 Human GDF-8
898089 Human GDF-15
898211 Human GFAP
894954 Human GM-CSF
898325 Human gp130
898410 Human Granzyme A
898137 Human Granzyme B
898081 Human Gro-a (CXCL1)
898092 Human Growth Hormone (GH)
898121 Human HE4/WFDC2
898483 Human Hepcidin
898061 Human HGF
898327 Human HGF R
898420 Human HIV-1 Gagp24
898774 Human HVEM
898093 Human ICAM-1
898790 Human IFN-beta
894955 Human IFN-gamma
898347 Human IGFBP-1
898457 Human IGFBP-2
894956 Human IL-10
898404 Human IL-11
894957 Human IL-12 p70
898094 Human IL-13
898095 Human IL-15
894959 Human IL-17A
894960 Human IL-18
898096 Human IL-18 Bpa
898055 Human IL-1a
894962 Human IL-1b
894961 Human IL-1ra/IL-1F3
894963 Human IL-2
898280 Human IL-3
898197 Human IL-33
894965 Human IL-34
894966 Human IL-4
894967 Human IL-5
894968 Human IL-6
898199 Human IL-6R alpha
894969 Human IL-7
894950 Human IL-8/CXCL8
898424 Human Insulin
898412 Human I-TAC
898469 Human Klotho
898736 Human LAG-3
898201 Human LBP
898249 Human Leptin
898274 Human Light
898097 Human Lipocalin-2/NGAL
898205 Human M-CSF
898119 Human Mesothelin
898141 Human MICA
898149 Human MIF
894970 Human MMP-1
898098 Human MMP-2
898207 Human MMP-7
894971 Human MMP-8
898099 Human MMP-9
898237 Human Myeloperoxidase (MPO)
898235 Human NCAM-1
898987 Human Neprilysin/CD10
898312 Human NF-H
898345 Human NGF R/TNFRSF16
898516 Human NT-3
898209 Human OPG
894972 Human Osteopontin (OPN)
898101 Human PCSK9
894973 Human PDGF-BB
898213 Human Pentraxin-3/TSG-14
898418 Human Periostin/OSF2
894974 Human PlGF
898497 Human Procalcitonin
898716 Human Pro-GRP
898100 Human Prolactin
898102 Human RAGE
898278 Human Rantes
898241 Human Reg3A
898219 Human Relaxin-2
898316 Human SCF
898921 Human Serpin A1
894975 Human Serpin A4
898223 Human Serpin E1/PAI-1
898239 Human SHH
898151 Human SLPI
898225 Human SP-D
898103 Human ST2/IL-1 R4
898414 Human TACI/TNFRSF13B
898416 Human TFF3
898477 Human TGF-B1
898229 Human Thrombospondin-1
894976 Human Tie-2
898062 Human TIM-1/KIM-1/HAVCR
898744 Human TIM-3
898104 Human TIMP-1
898105 Human TNF R1
898106 Human TNF RII
894977 Human TNF-alpha
898063 Human TNF-b
898063 Human TNF-beta
898067 Human Total Adiponectin/Acrp30
898276 Human Trail
898343 Human Trappin-2/Elafin
898622 Human TREM-1
898314 Human TWEAK
898122 Human uPA-1
898107 Human VCAM-1
894978 Human VEGF A
898108 Human VEGF R1
898064 Human VEGF R2/KDR
898422 Human VEGF-B
898231 Human VEGF-C
898109 Human Vitamin D BP
630-XX2 Lyophilized Control
630-XX4 Lyophilized Control
630-XX1 Lyophilized Control
630-XX3 Lyophilized Control
898305 Mouse CCL2/MCP-1/JE
898559 Mouse CXCL10/IP-10
898561 Mouse CXCL12/SDF-1a
898306 Mouse CXCL2/MIP-2
898640 Mouse CXCL9/MIG
898610 Mouse GM-CSF
898307 Mouse IL-6
898308 Mouse TNF-alpha
898702 Mouse VEGF A
898389 Rat Cystatin C
898391 Rat Lipocalin-2/NGAL
898393 Rat Osteopontin (OPN)
898395 Rat TIM-1/KIM-1/HAVCR
896198 Sample Diluent SD21
610-XXX Sample Diluent
610-017 Sample Diluent SD17
610-020 Sample Diluent SD20
610-010 Sample Diluent SD10
610-009 Sample Diluent SD09
610-011 Sample Diluent SD11
610-012 Sample Diluent SD12
610-016 Sample Diluent SD16
610-006 Sample Diluent SD06
896098 Sample Diluent SD13
896199 Sample Diluent SD28
896099 Sample Diluent SD30
610-001 WASH BUFFER
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