Thin-Layer Chromatography Plates
TLC is a commonly used method development tool for flash purification. Product mixtures separated using TLC generally can be purified by flash chromatography using the identical solvent system.
TLC to flash method transfer accuracy is improved when TLC plates and flash cartridges with identical silica from Biotage are used. For synthetic chemists, the benefits of matched TLC plates and flash cartridges are better purification throughput, increased compound purity and yield, and reduced solvent cost.